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Isosorbide is used to prevent or treat chest pain (angina). It works by relaxing the blood vessels to the heart so the blood and oxygen supply to the heart is increased.Isosorbide controls chest pain but does not cure it. Continue to take isosorbide even if you feel well. Do not stop taking isosorbide without talking to your doctor. Stopping the drug abruptly may cause chest pain.Isosorbide tablets are also used with other drugs to treat congestive heart failure.

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