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Category : Antispasmodic; smooth muscle relaxant. Mebeverine has a direct non-specific relaxant effect on vascular cardiac and other smooth muscle. Studies indicate that the spasmolytic activity of mebeverine is not restricted to one particular system but the compound possesses a polyvalent spasmolytic action in which at least three types of mechanisms are involved:- a direct musculotropic action involving calcium ion exchange and stabilization of excitable membranes- a competitive antimuscarinic activity of about 0.05 - 0.1 times that of atropine- a local anaesthetic activity together with potentiation of sympathetic inhibitory influences due to blockade of noradrenaline uptake into sympathetic nerve endings
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About COLOSPA Colofac:
Product Type: Prescription Drugs 4
COLOSPA ( Colofac Generic Mebeverine )
COLOSPA (Colofac Generic Mebeverine)
Colofac Generic Mebeverine
135mg 135mg Tabs 4 x 100 Tablets 100 Tablets 2 x 100 Tablets 30 (3 x 10)
Colofac Generic Mebeverine COLOSPA

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